Release Notes — GastroPlusGPT™ v1.1
Simulations Plus, Inc. (NASDAQ: SLP)
P.O. Box 12317 | Research Triangle Park | NC | 27709 | United States
Office: +1-661-723-7723 | info@simulations-plus.com | www.simulations-plus.com
GastroPlus® X.2 – 2025 Release Notes
August 28, 2025
Dear GastroPlus® User,
We are excited to launch GastroPlusGPT™—a suite of AI-powered tools—alongside our 2025 release of GastroPlus® X (GPX™) platform. GastroPlusGPT™ introduces three innovative new tools to enhance scientific analysis, streamline model building, and improve the overall GastroPlus user experience.
AI-powered Apps
GastroPlusChat™
GastroPlusChat™ is an LLM-powered assistant designed to help users quickly access insights from GastroPlus documentation and tutorials, providing instant answers to technical and procedural questions related to the GastroPlus®X (GPX™) software ecosystem.
Data Extractor
The Data Extractor enables users to extract structured, machine-readable data from images of tables and plots, automating the digitization process of scientific and pharmacokinetic data.
AssessmentsPlus AI™
AssessmentsPlus AI™ is an AI-powered enhancement to the AssessmentsPlus™ module in GastroPlus®X, providing a report-friendly summary, visualization of key compound properties and simulation results, and modeling recommendations. It comes complete with an integrated chatbot that answers questions about your compound, simulation, and any recommended actions in GastroPlus®X.
Access
Access to these tools is included with your GastroPlus® license via this link: GastroPlusGPT™.
To request login credentials, please click on the “Sign up to request access” button on the landing page.

Getting Help
For any assistance, enhancement ideas, or questions, please contact:
📧 support@simulations-plus.com
🌐 www.simulations-plus.com
📞 +1-661-723-7723
Thank you for your continued support of GastroPlus®. We remain committed to delivering innovation, accuracy, and excellence for your modeling and simulation needs.
Sincerely,
Simulations Plus, Inc.